Stem cell scientists and bioengineers are now capable of generating new synthetic living models of human biology. These quasi-human entities do not fit into any of the existing approaches for bioethics guidelines and review. Professor Hyun will collaborate with three major labs working in this field to create a normative framework for defining ethical bioengineering goals and practices in synthetic modeling research. This will help promote the ethical advancement of this new area of biomedical research.
Our Grants
A Collaborative Ethical Approach to Advancing the Science of Synthetic Living Models of Human Biology
Insoo Hyun, PhD
Case Western Reserve University
Case Western Reserve University
Grant Type
Making a Difference
Grant Cycle
fall 2018
Duration
2 Years
Amount
$148,997
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Jeantine E. Lunshof, Brain Surrogates—Empty or Full Makes the Difference, The American Journal of Bioethics, Dec 2020.
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Elena Garreta et al., Rethinking organoid technology through bioengineering, nature materials, November 2020.
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M Levin et al., Applications and ethics of computer-designed organisms, Nature Reviews Molecular Cell Biology, Aug 2020.
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Insoo Hyun et al., Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells, Stem Cell Reports, Feb 2020.
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Insoo Hyun, Ethical considerations for human-animal neurological chimera research: mouse models and beyond, The EMBO Journal, Nov 2019.
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Grant Focus Areas
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