Stem cell scientists and bioengineers are now capable of generating new synthetic living models of human biology. These quasi-human entities do not fit into any of the existing approaches for bioethics guidelines and review. Professor Hyun will collaborate with three major labs working in this field to create a normative framework for defining ethical bioengineering goals and practices in synthetic modeling research. This will help promote the ethical advancement of this new area of biomedical research.
A Collaborative Ethical Approach to Advancing the Science of Synthetic Living Models of Human Biology
Case Western Reserve University
M Levin et al., Applications and ethics of computer-designed organisms, Nature Reviews Molecular Cell Biology, Aug 2020.Read more
Insoo Hyun et al., Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells, Stem Cell Reports, Feb 2020.Read more
Insoo Hyun, Ethical considerations for human-animal neurological chimera research: mouse models and beyond, The EMBO Journal, Nov 2019.Read more