The HIV Organ Policy Equity Act now permits transplanting organs from HIV+ donors to HIV+ recipients. This project will examine the ethical issues faced by this novel practice in actual clinical settings so that such transplants are responsibly and appropriately performed. First, we will collect in-depth qualitative data from the early recipients of HIV+/HIV+ transplants as well as those patients living with HIV who are offered an HIV+ organ and refuse. In addition, we will survey patients living with HIV who are on an organ waitlist regarding their knowledge, attitudes and beliefs about HIV+ transplants. The aggregate data will be used to help create patient-reported outcome measures of ethics outcomes as well as a standardized informed consent process and guidance for independent recipient advocates. These tools will be implemented in a multicenter clinical trial and disseminated through peer-reviewed publications as well as professional conferences and networks.
Addressing the Ethical Issues in HIV+ to HIV+ Organ Transplants
Johns Hopkins University
Santi M. Seaman et al., Willingness to accept HIV-infected and increased infectious risk donor organs among transplant candidates living with HIV, JAIDS: Journal of Acquired Immune Deficiency Syndromes, May 2020.Read more
Juli M. Bollinger et al., Early experiences of independent advocates for potential HIV+ recipients of HIV+ donor organ transplants, Clinical Transplantation, July 2019.Read more